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Engineering    2017, Vol. 3 Issue (1) : 3 -15
Research |
Noncoding RNAs and Their Potential Therapeutic Applications in Tissue Engineering
Shiying Li,Tianmei Qian,Xinghui Wang,Jie Liu,Xiaosong Gu()
Key Laboratory of Neuroregeneration of Jiangsu and the Ministry of Education, Co-Innovation Center of Neuroregeneration, Nantong University, Nantong, Jiangsu 226001, China

Tissue engineering is a relatively new but rapidly developing field in the medical sciences. Noncoding RNAs (ncRNAs) are functional RNA molecules without a protein-coding function; they can regulate cellular behavior and change the biological milieu of the tissue. The application of ncRNAs in tissue engineering is starting to attract increasing attention as a means of resolving a large number of unmet healthcare needs, although ncRNA-based approaches have not yet entered clinical practice. In-depth research on the regulation and delivery of ncRNAs may improve their application in tissue engineering. The aim of this review is: to outline essential ncRNAs that are related to tissue engineering for the repair and regeneration of nerve, skin, liver, vascular system, and muscle tissue; to discuss their regulation and delivery; and to anticipate their potential therapeutic applications.

Keywords Tissue engineering      Noncoding RNAs      MicroRNAs      Nerve      Skin      Liver      Vascular system      Muscle     
Corresponding Authors: Xiaosong Gu   
Just Accepted Date: 16 February 2017   Online First Date: 28 February 2017    Issue Date: 02 March 2017
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Shiying Li
Tianmei Qian
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Xiaosong Gu
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Shiying Li,Tianmei Qian,Xinghui Wang, et al. Noncoding RNAs and Their Potential Therapeutic Applications in Tissue Engineering[J]. Engineering, 2017, 3(1): 3 -15 .
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