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Adoptive cell transfer therapy for hepatocellular carcinoma
Renyu Zhang, Zhao Zhang, Zekun Liu, Ding Wei, Xiaodong Wu, Huijie Bian, Zhinan Chen
Frontiers of Medicine 2019, Volume 13, Issue 1, Pages 3-11 doi: 10.1007/s11684-019-0684-x
Keywords: adoptive cell transfer therapy hepatocellular carcinoma T cell chimeric antigen receptor immunotherapy
Frontiers of Medicine 2022, Volume 16, Issue 3, Pages 322-338 doi: 10.1007/s11684-021-0901-2
Keywords: immunotherapy chimeric antigen receptor solid tumors tumor-associated antigen glycosylation O-glycans adoptivecell therapy
Challenges of NK cell-based immunotherapy in the new era
Fang Fang, Weihua Xiao, Zhigang Tian
Frontiers of Medicine 2018, Volume 12, Issue 4, Pages 440-450 doi: tzg@ustc.edu.cn
Keywords: natural killer cells immunotherapy adoptive transfer genetic modification immune checkpoint inhibitor
Stem cell gene therapy: the risks of insertional mutagenesis and approaches to minimize genotoxicity
Chuanfeng Wu, Cynthia E. Dunbar
Frontiers of Medicine 2011, Volume 5, Issue 4, Pages 356-371 doi: 10.1007/s11684-011-0159-1
Keywords: gene therapy hematopoietic stem cells insertional mutagenesis genotoxicity induced pluripotent stem cell
Frontiers of Medicine 2022, Volume 16, Issue 6, Pages 827-858 doi: 10.1007/s11684-022-0948-8
Keywords: infertility stem cell therapy mesenchymal stem cells pluripotent stem cells
Molecular markers and pathogenically targeted therapy in non-small cell lung cancer
Bo PENG BA , Jinnong ZHANG MD , Jamile S. WOODS MD , Wei PENG MD, PhD
Frontiers of Medicine 2009, Volume 3, Issue 3, Pages 245-255 doi: 10.1007/s11684-009-0044-3
Keywords: lung cancer carcinoma non-small cell lung cancer molecular markers targeted therapy
A giant step forward: chimeric antigen receptor T-cell therapy for lymphoma
Houli Zhao, Yiyun Wang, Elaine Tan Su Yin, Kui Zhao, Yongxian Hu, He Huang
Frontiers of Medicine 2020, Volume 14, Issue 6, Pages 711-725 doi: 10.1007/s11684-020-0808-3
Keywords: chimeric antigen receptor T (CAR-T) cell lymphoma cytokine release syndrome (CRS) immune effector cell-associated
Anlotinib as third- or further-line therapy for short-term relapsed small-cell lung cancer: subgroup
Frontiers of Medicine 2022, Volume 16, Issue 5, Pages 766-772 doi: 10.1007/s11684-021-0916-8
Keywords: anlotinib chemotherapy short-term relapsed small-cell lung cancer
Chemical transdifferentiation: closer to regenerative medicine
Aining Xu,Lin Cheng
Frontiers of Medicine 2016, Volume 10, Issue 2, Pages 152-165 doi: 10.1007/s11684-016-0445-z
Cell transdifferentiation, which directly switches one type of differentiated cells into another celltype, is more advantageous than cell reprogramming to generate pluripotent cells and differentiate themdevelopments in the research of small molecules in promoting cell conversion.Particularly, we focus on the complete chemical compound-induced cell transdifferentiation, which iscloser to the clinical translation in cell therapy.
Keywords: cell therapy cell transdifferentiation chemical compounds small molecules tissue regeneration
Precision medicine in acute lymphoblastic leukemia
Ching-Hon Pui
Frontiers of Medicine 2020, Volume 14, Issue 6, Pages 689-700 doi: 10.1007/s11684-020-0759-8
Keywords: acute lymphoblastic leukemia molecular therapeutics targeted therapy tyrosine kinase inhibitors immunotherapy CAR T-cell therapy
Chinese expert consensus on oral drugs for the treatment of mature B-cell lymphomas (2020 edition)
Frontiers of Medicine 2022, Volume 16, Issue 5, Pages 815-826 doi: 10.1007/s11684-021-0891-0
Keywords: B-cell lymphoma oral drug targeted therapy immunotherapy COVID-19 pandemic
The regulatory sciences for stem cell-based medicinal products
Bao-Zhu Yuan,Junzhi Wang
Frontiers of Medicine 2014, Volume 8, Issue 2, Pages 190-200 doi: 10.1007/s11684-014-0323-5
Over the past few years, several new achievements have been made from stem cell studies, many of whichMoreover, some stem cell-based products have been approved for marketing by different national regulatoryHowever, many critical issues associated mainly with incomplete understanding of stem cell biology andIn this review, we summarize some new achievements in stem cell studies, especially the preclinical andabreast of evolvement of stem cell sciences and technologies.
Keywords: stem cell-based medicinal products (SCMPs) stem cell therapy (SCT) safety effectiveness standards guidelines
EBV-associated lymphoproliferative disease post-CAR-T cell therapy
Frontiers of Medicine 2024, Volume 18, Issue 2, Pages 394-398 doi: 10.1007/s11684-023-1032-8
Keywords: EBV-associated lymphoproliferative disease chimeric antigen receptor T-cell autologous stem cell transplantation
Macroencapsulation Devices for Cell Therapy Review
Wei Liu,Yanfang Wang,Jinqiang Wang,Olivia L. Lanier,Marissa E. Wechsler,Nicholas A. Peppas,Zhen Gu
Engineering 2022, Volume 13, Issue 6, Pages 53-70 doi: 10.1016/j.eng.2021.10.021
Macroencapsulation has been widely used in cell therapy due to its capability to provide immune-privilegedMacroencapsulation also serve to provide mechanical and physiochemical support for maintaining cell expansionRecent studies focus on expanding the applications of these devices to new cell-based areas such as chimericantigen receptor (CAR)-T cell delivery, cardiovascular disease therapy, and the exploration of new materials, construction methods, and working principles to augment treatment efficacy and prolong therapy duration
Keywords: Drug delivery Cell encapsulation Cell therapy Cell transplantation Biomedical devices
NADPH oxidase and reactive oxygen species as signaling molecules in carcinogenesis
Gang WANG
Frontiers of Medicine 2009, Volume 3, Issue 1, Pages 1-7 doi: 10.1007/s11684-009-0018-5
Keywords: free radicals tumor phox cell proliferation cancer therapy
Title Author Date Type Operation
Adoptive cell transfer therapy for hepatocellular carcinoma
Renyu Zhang, Zhao Zhang, Zekun Liu, Ding Wei, Xiaodong Wu, Huijie Bian, Zhinan Chen
Journal Article
CAR T cells redirected against tumor-specific antigen glycoforms: can low-sugar antigens guarantee a sweet success?
Journal Article
Challenges of NK cell-based immunotherapy in the new era
Fang Fang, Weihua Xiao, Zhigang Tian
Journal Article
Stem cell gene therapy: the risks of insertional mutagenesis and approaches to minimize genotoxicity
Chuanfeng Wu, Cynthia E. Dunbar
Journal Article
Cell therapy for the treatment of reproductive diseases and infertility: an overview from the mechanism
Journal Article
Molecular markers and pathogenically targeted therapy in non-small cell lung cancer
Bo PENG BA , Jinnong ZHANG MD , Jamile S. WOODS MD , Wei PENG MD, PhD
Journal Article
A giant step forward: chimeric antigen receptor T-cell therapy for lymphoma
Houli Zhao, Yiyun Wang, Elaine Tan Su Yin, Kui Zhao, Yongxian Hu, He Huang
Journal Article
Anlotinib as third- or further-line therapy for short-term relapsed small-cell lung cancer: subgroup
Journal Article
Chinese expert consensus on oral drugs for the treatment of mature B-cell lymphomas (2020 edition)
Journal Article
The regulatory sciences for stem cell-based medicinal products
Bao-Zhu Yuan,Junzhi Wang
Journal Article
Macroencapsulation Devices for Cell Therapy
Wei Liu,Yanfang Wang,Jinqiang Wang,Olivia L. Lanier,Marissa E. Wechsler,Nicholas A. Peppas,Zhen Gu
Journal Article