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Can intravesical bacillus Calmette-Guérin reduce recurrence in patients with non-muscle invasive bladder

Jiangang Pan,Mo Liu,Xing Zhou

Frontiers of Medicine 2014, Volume 8, Issue 2,   Pages 241-249 doi: 10.1007/s11684-014-0328-0

Abstract: Bacillus Calmette-Guérin (BCG) instillation and maintenance is considered as the standard adjuvantA number of randomized studies have focused on the benefit of maintenance therapy following initial BCGEvidence suggested that adjuvant intravesical BCG with maintenance treatment is significantly effective

Keywords： non-muscle invasive bladder cancer     bacillus Calmette-Guérin (BCG)     meta-analysis    

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Testing of tuberculosis infection among Chinese adolescents born after terminating the Bacillus Calmette--Guérin booster vaccination: subgroup analysis of a population-based cross-sectional study

Hengjing Li, Henan Xin, Shukun Qian, Xiangwei Li, Haoran Zhang, Mufei Li, Boxuan Feng, Qi Jin, Lei Gao

Frontiers of Medicine 2017, Volume 11, Issue 4,   Pages 528-535 doi: 10.1007/s11684-017-0573-0

Abstract:

The prevalence of tuberculosis infection among adolescents born after terminating the Bacillus Calmette–Guérin (BCG) booster vaccination in China was estimated using tuberculin skin testing (TST) and QuantiFERON-TB Gold assay (QFT) to investigate the influence of neonatal BCG vaccination onOnly TST was positively associated with BCG vaccination with an adjusted odds ratio of 1.71 [95% confidenceOur results suggested that BCG neonatal vaccination still affects TST performance, and a two-step approach

Keywords： tuberculin skin test     interferon-γ release assays     adolescent     agreement    

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A meta-analysis of randomized trials of maintenance bacillus Calmette-Guerin instillation efficacy against

PAN Jiangang, ZHOU Xing, CHEN Zhiguang, HAN Ruifa

Frontiers of Medicine 2008, Volume 2, Issue 3,   Pages 259-263 doi: 10.1007/s11684-008-0049-3

Abstract: Meta-analysis was used to determine whether maintenance intravesical bacillus Calmette-Guerin (BCG) couldavailable published data of randomized clinical trials comparing transurethral resection plus intravesical BCGWithin the follow-up period, 375 of 915 (41.0%) BCG-treated patients and 332 of 733 (45.3%) non-BCG-treatedmeta-analysis did not show any statistically significant confounding effects on the results when stratified by BCGTherefore, we came to the conclusion that adjuvant maintenance instillation BCG combined with transurethral
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Study of recombinant human IFN-α-2b bacilli Calmette–Guerin activated killer cells and against bladder

FAN Xiaodong, HAN Ruifa

Frontiers of Medicine 2007, Volume 1, Issue 4,   Pages 377-380 doi: 10.1007/s11684-007-0073-8

Abstract: Presently, one of the most potent immunotherapies is the application of bacillus Calmette Guerin (BCGTherefore, current studies aim at developing recombinant BCG (rBCG) strains secreting Th1-like cytokinesPeripheral blood monocytes (PBMC) were stimulated by recombinant BCG and transformed into bacilli Calmette–GuerinRecombinant IFN--2b-BCG, wild-type BCG (wBCG), wild-type BCG and IFN--2b were coincubated with PBMCsWe conclude that the recombinant BCG can activate more PBMCs to anti-bladder cancer than wild-type BCG

Keywords： Urology     powerful     2b-BCG     Tianjin institute     wild-type    

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Telomeric impact of conventional chemotherapy

Yiming Lu, Waiian Leong, Olivier Guérin, Eric Gilson, Jing Ye

Frontiers of Medicine 2013, Volume 7, Issue 4,   Pages 411-417 doi: 10.1007/s11684-013-0293-z

Abstract:

The increased level of chromosome instability in cancer cells, leading to aneuploidy and gross chromosomal rearrangements, is not only a driving force for oncogenesis but also can be the Achille’s heel of the disease since many chemotherapies (CT) kill cells by inducing a non-tolerable rate of DNA damage. A wealth of published evidence showed that telomere stability can be more affected than the bulk of the genome by several conventional antineoplasic drugs. These results raise the interesting possibility that CT with genotoxic drugs preferentially target telomeres. In agreement with this view, accelerated shortening of telomere length has been described in blood lineage cells following high-dose CT (stem cell transplantation) or non-myeloablative CT. However, almost nothing is known on the consequences of this shortening in terms of telomere stability, senescence and on the development of second cancers or post-treatment aging-like syndromes in cancer survivors (cognitive defect, fertility impairment, etc.). In this article, we propose: (1) telomeres of cancer cells are preferential genomic targets of chemotherapies altering chromosome maintenance; (2) telomere functional parameters can be a surrogate marker of chemotherapy sensitivity and toxicity; (3) the use of anti-telomere molecule could greatly enhance the sensitivity to standards chemotherapies.

Keywords： telomere     antineoplasic drugs     conventional chemotherapies    

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Characterization of Bacillus amyloliquefacien contaminating 75% alcohol disinfectant

ZHANG Wanming, YUAN Yuesha, BIAN Cangli, TU Xianyu, ZHANG Wen, HUANG Huqiang, WANG Lan

Frontiers of Medicine 2008, Volume 2, Issue 1,   Pages 113-116 doi: 10.1007/s11684-008-0021-2

Abstract: The clinical characterization of Bacillus amyloliquefacien contaminating 75% alcohol disinfectants wereTheir total number was more than 800 cfu/mL and they were identified as Bacillus amyloliquefacien.It was suggested that alcohol disinfectant fluid was easily contaminated by Bacillus amyloliquefacien
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Use of dry yeast cells as a cheap nitrogen source for lactic acid production by thermophilic

Kim Yng Ooi, Jin Chuan Wu

Frontiers of Chemical Science and Engineering 2015, Volume 9, Issue 3,   Pages 381-385 doi: 10.1007/s11705-015-1534-2

Abstract: Dry yeast cells (DYC) were used as a cheap nitrogen source to replace expensive yeast extract (YE) for L-lactic acid production by thermophilic . Cassava starch (200 g·L ) was converted to L-lactic acid by simultaneous saccharification and fermentation using WCP10-4 at 50 °C in the presence of 20 g·L of DYC, giving 148.1 g·L of L-lactic acid at 27 h with a productivity of 5.5 g·L ·h and a yield of 92%. In contrast, 154.4 g·L of lactic acid was produced at 24 h with a productivity of 6.4 g·L ·h and a yield of 96% when equal amount of YE was used under the same conditions. Use of pre-autolyzed DYC at 50 °C for overnight slightly improved the lactic acid titer (154.5 g·L ) and productivity (7.7 g·L ·h ) but gave the same yield (96%).

Keywords： L-lactic acid     thermophilic strain     Bacillus coagulans     dry yeast cells     autolysis     fermentation    

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Chromium phytoextraction and physiological responses of the hyperaccumulator Swartz to plant growth-promoting rhizobacterium inoculation

Frontiers of Environmental Science & Engineering 2023, Volume 17, Issue 1, doi: 10.1007/s11783-023-1609-0

Abstract:

● Improved Cr phytoextration efficiency was achieved by B. cereus inoculation.

Keywords： Hexavalent chromium     Hyperaccumulator     Rhizobacteria     Leersia hexandra Swartz     Bacillus cereus    

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Physicochemical Properties and Bioactivities of Rice Beans Fermented by Bacillus amyloliquefaciens Article

Shan Wu,  Shuai Lu, Jun Liu, Shaoqing Yang, Qiaojuan Yan, Zhengqiang Jiang

Engineering 2021, Volume 7, Issue 2,   Pages 219-225 doi: 10.1016/j.eng.2020.10.010

Abstract: physicochemical properties and bioactivities of rice beans (Vigna umbellata) fermented by BacillusRice beans fermented by Bacillus amyloliquefaciens may serve as a functional food with potential

Keywords： Solid-state fermentation     Rice beans     Bacillus amyloliquefaciens     Antithrombotic activity     Antioxidant    

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Feasibility of Scaling up the Cost-Competitive and Clean Electrolytic Hydrogen Supply in China

Guangsheng Pan,Wei Gu,Zhongfan Gu,Jin Lin,Suyang Zhou,Zhi Wu,Shuai Lu,

Engineering doi: 10.1016/j.eng.2024.05.014

Abstract: Scaling up clean hydrogen supply in the near future is critical to achieving China’s hydrogen development target. This study established an electrolytic hydrogen development mechanism considering the generation mix and operation optimization of power systems with access to hydrogen. Based on the incremental cost principle, we quantified the provincial and national clean hydrogen production cost performance levels in 2030. The results indicated that this mechanism could effectively reduce the production cost of clean hydrogen in most provinces, with a national average value of less than 2 USD·kg−1 at the 40-megaton hydrogen supply scale. Provincial cooperation via power transmission lines could further reduce the production cost to 1.72 USD·kg−1. However, performance is affected by the potential distribution of hydrogen demand. From the supply side, competitiveness of the mechanism is limited to clean hydrogen production, while from the demand side, it could help electrolytic hydrogen fulfil a more significant role. This study could provide a solution for the ambitious development of renewables and the hydrogen economy in China.

Keywords： Low-carbon energy system     Electrolytic hydrogen     Renewables     Cost optimization and analysis    

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Experimental study on the efficacy of Fuganling granula on protecting against immunological hepatic injury

Yanli LIU, Rong LIU, Cheng ZHEN, Quanfang GUO, Liping WU, Zhaoxi DING, Yushun BI, Zhiyu LIU

Frontiers of Medicine 2009, Volume 3, Issue 1,   Pages 91-95 doi: 10.1007/s11684-009-0011-z

Abstract: Fuganling granula (FGL, 复肝灵颗粒) in treating mouse immunological hepatic injury that was caused by Bacille CalmetteGuerin (BCG) and lipopolysaccharide (LPS), a total of 60 mice were adopted, among which, 50 mice weregiven intraperitoneal injection with BCG and LPS to establish an immunological liver injury model and

Keywords： Fuganling granula     immunological liver injury     bacille calmette guerin     lipopolysaccharide     mice    

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Effect of calcium lactate on compressive strength and self-healing of cracks in microbial concrete

Kunamineni VIJAY, Meena MURMU

Frontiers of Structural and Civil Engineering 2019, Volume 13, Issue 3,   Pages 515-525 doi: 10.1007/s11709-018-0494-2

Abstract: This paper presents the effect on compressive strength and self-healing capability of bacterial concrete with the addition of calcium lactate. Compared to normal concrete, bacterial concrete possesses higher durability and engineering concrete properties. The production of calcium carbonate in bacterial concrete is limited to the calcium content in cement. Hence calcium lactate is externally added to be an additional source of calcium in the concrete. The influence of this addition on compressive strength, self-healing capability of cracks is highlighted in this study. The bacterium used in the study is and was added to both spore powder form and culture form to the concrete. spore powder of 2 million cfu/g concentration with 0.5% cement was mixed to concrete. Calcium lactates with concentrations of 0.5%, 1.0%, 1.5%, 2.0%, and 2.5% of cement, was added to the concrete mixes to test the effect on properties of concrete. In other samples, cultured with a concentration of 1×10 cells/mL was mixed with concrete, to study the effect of bacteria in the cultured form on the properties of concrete. Cubes of 100 mm×100 mm×100 mm were used for the study. These cubes were tested after a curing period of 7, 14 and 28 d. A maximum of 12% increase in compressive strength was observed with the addition of 0.5% of calcium lactate in concrete. Scanning electron microscope and energy dispersive X-ray spectroscopy examination showed the formation of ettringite in pores; calcium silicate hydrates and calcite which made the concrete denser. A statistical technique was applied to analyze the experimental data of the compressive strengths of cementations materials. Response surface methodology was adopted for optimizing the experimental data. The regression equation was yielded by the application of response surface methodology relating response variables to input parameters. This method aids in predicting the experimental results accurately with an acceptable range of error. Findings of this investigation indicated the influence of added calcium lactate in bio-concrete which is quite impressive for improving the compressive strength and self-healing properties of concrete.

Keywords： calcium lactate     bacillus subtilis     compressive strength     self-healing of cracks    

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Roles of acid-producing bacteria in anaerobic digestion of waste activated sludge

Sijia Ai, Hongyu Liu, Mengjie Wu, Guangming Zeng, Chunping Yang

Frontiers of Environmental Science & Engineering 2018, Volume 12, Issue 6, doi: 10.1007/s11783-018-1050-y

Abstract:

Bacillus coagulans improved TCOD removal

The optimal inoculum concentration of Bacillus

Keywords： Anaerobic digestion     Waste activated sludge     Acid-producing bacteria     Bacillus coagulans    

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Climate change and China’s mega urban regions

Chaolin GU, Sunsheng HAN

Frontiers of Structural and Civil Engineering 2010, Volume 4, Issue 4,   Pages 418-430 doi: 10.1007/s11709-010-0075-5

Abstract: China’s mega urban regions are focal points of economic development and environmental concerns. This paper positions four mega urban regions (i.e., the Yangtze River Delta, the Pearl River Delta, the Bohai Bay Area, and the South-eastern Fujian Province) along China’s coast into the national economy and elaborates their development challenges and planning innovations. Mega urban regions in China are spatial consequences of rapid economic transition. They deserve close scrutiny and demands for innovative planning responses in order to maintain their key role in driving economic growth but limiting their greenhouse gas emission.

Keywords： climate change     mega urban region     urban planning    

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Design of damping valve for vehicle hydro pneumatic suspension

DONG Mingming, HUANG Hua, GU Lian

Frontiers of Mechanical Engineering 2008, Volume 3, Issue 1,   Pages 97-100 doi: 10.1007/s11465-008-0014-5

Abstract: According to the design features of a hydro pneumatic spring, the necessity of a separate damping valve is proposed. Based on a 1/4 vehicle linear suspension model, the optimum damping coefficient is worked out and the parameters of the damping valve are determined with the equivalent linearization method. A practical structure of the damping valve is proposed having a small size, high flowrate when the valve opens, and the ability of enduring high back pressure. Based on bench tests, the damping valve has been found to properly work and be suitable. The design method and damping valve structure are useful guides for hydro pneumatic suspension, especially for the design of heavy-duty vehicles.

Keywords： ability     pneumatic     necessity     flowrate     equivalent linearization    

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Title Author Date Type Operation

Can intravesical bacillus Calmette-Guérin reduce recurrence in patients with non-muscle invasive bladder

Jiangang Pan,Mo Liu,Xing Zhou

Journal Article

Testing of tuberculosis infection among Chinese adolescents born after terminating the Bacillus Calmette--Guérin booster vaccination: subgroup analysis of a population-based cross-sectional study

Hengjing Li, Henan Xin, Shukun Qian, Xiangwei Li, Haoran Zhang, Mufei Li, Boxuan Feng, Qi Jin, Lei Gao

Journal Article

A meta-analysis of randomized trials of maintenance bacillus Calmette-Guerin instillation efficacy against

PAN Jiangang, ZHOU Xing, CHEN Zhiguang, HAN Ruifa

Journal Article

Study of recombinant human IFN-α-2b bacilli Calmette–Guerin activated killer cells and against bladder

FAN Xiaodong, HAN Ruifa

Journal Article

Telomeric impact of conventional chemotherapy

Yiming Lu, Waiian Leong, Olivier Guérin, Eric Gilson, Jing Ye

Journal Article

Characterization of Bacillus amyloliquefacien contaminating 75% alcohol disinfectant

ZHANG Wanming, YUAN Yuesha, BIAN Cangli, TU Xianyu, ZHANG Wen, HUANG Huqiang, WANG Lan

Journal Article

Use of dry yeast cells as a cheap nitrogen source for lactic acid production by thermophilic

Kim Yng Ooi, Jin Chuan Wu

Journal Article

Chromium phytoextraction and physiological responses of the hyperaccumulator Swartz to plant growth-promoting rhizobacterium inoculation

Journal Article

Physicochemical Properties and Bioactivities of Rice Beans Fermented by Bacillus amyloliquefaciens

Shan Wu,  Shuai Lu, Jun Liu, Shaoqing Yang, Qiaojuan Yan, Zhengqiang Jiang

Journal Article

Feasibility of Scaling up the Cost-Competitive and Clean Electrolytic Hydrogen Supply in China

Guangsheng Pan,Wei Gu,Zhongfan Gu,Jin Lin,Suyang Zhou,Zhi Wu,Shuai Lu,

Journal Article

Experimental study on the efficacy of Fuganling granula on protecting against immunological hepatic injury

Yanli LIU, Rong LIU, Cheng ZHEN, Quanfang GUO, Liping WU, Zhaoxi DING, Yushun BI, Zhiyu LIU

Journal Article

Effect of calcium lactate on compressive strength and self-healing of cracks in microbial concrete

Kunamineni VIJAY, Meena MURMU

Journal Article

Roles of acid-producing bacteria in anaerobic digestion of waste activated sludge

Sijia Ai, Hongyu Liu, Mengjie Wu, Guangming Zeng, Chunping Yang

Journal Article

Climate change and China’s mega urban regions

Chaolin GU, Sunsheng HAN

Journal Article

Design of damping valve for vehicle hydro pneumatic suspension

DONG Mingming, HUANG Hua, GU Lian

Journal Article