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Jiong HU
Frontiers of Medicine 2011, Volume 5, Issue 1, Pages 45-52 doi: 10.1007/s11684-011-0117-y
Acute promyelocytic leukemia (APL) is a subtype of acute myeloid leukemia.directly degrades the PML-RARα fusion transcript, leading to the differentiation and apoptosis of leukemiacells and the potential eradication of APL leukemia-initiating cells (LICs), thus making the diseasea potentially curable type of leukemia.
Keywords: acute promyelocytic leukemia arsenic all-trans retinoic acid survival
Molecular pathogenesis of acute myeloid leukemia: A diverse disease with new perspectives
Felicitas THOL, Arnold GANSER
Frontiers of Medicine 2010, Volume 4, Issue 4, Pages 356-362 doi: 10.1007/s11684-010-0220-5
Keywords: acute myeloid leukemia mutations risk stratification
Prognostic analysis of chronic myeloid leukemia in Chinese population in an imatinib era
Haiyan He, Yang Shen, Yongmei Zhu, Saijuan Chen
Frontiers of Medicine 2012, Volume 6, Issue 2, Pages 204-211 doi: 10.1007/s11684-012-0202-x
We evaluated the outcomes of chronic myeloid leukemia (CML) patients in three clinical phases, namely
Keywords: imatinib chronic myeloid leukemia complete cytogenetic response
FGF13 suppresses acute myeloid leukemia by regulating bone marrow niches
Frontiers of Medicine 2022, Volume 16, Issue 6, Pages 896-908 doi: 10.1007/s11684-022-0944-z
Keywords: acute myeloid leukemia FGF13 prognosis immune-related genes bone marrow niches
Lanping Xu,Huanling Zhu,Jianda Hu,Depei Wu,Hao Jiang,Qian Jiang,Xiaojun Huang
Frontiers of Medicine 2015, Volume 9, Issue 3, Pages 304-311 doi: 10.1007/s11684-015-0400-4
Keywords: chronic myeloid leukemia imatinib dasatinib nilotinib allogeneic hematopoietic stem cell transplantation
Molecular mechanisms of leukemia-associated protein degradation
Ying-Li WU, Guo-Qiang CHEN, Hu-Chen ZHOU,
Frontiers of Medicine 2010, Volume 4, Issue 4, Pages 363-370 doi: 10.1007/s11684-010-0210-7
Keywords: protein degradation leukemia chemical biology transcription factors oncoprotein
Early T-cell precursor leukemia: a subtype of high risk childhood acute lymphoblastic leukemia
Meilin Ma, Xiang Wang, Jingyan Tang, Huiliang Xue, Jing Chen, Ci Pan, Hua Jiang, Shuhong Shen
Frontiers of Medicine 2012, Volume 6, Issue 4, Pages 416-420 doi: 10.1007/s11684-012-0224-4
Acute lymphoblastic leukemia includes T-cell acute lymphoblastic leukemia (T-ALL) and B-cell acutelymphoblastic leukemia (B-ALL).This novel subtype of T-ALL was called early T-cell precursor acute lymphoblastic leukemia (ETP-ALL).Our findings demonstrate that early T-cell precursor leukemia is a very high-risk subtype of acute lymphoblasticleukemia with poor prognosis.
Keywords: acute lymphoblastic leukemia early T precursor prognosis
Yuting Tan,Han Liu,Saijuan Chen
Frontiers of Medicine 2015, Volume 9, Issue 4, Pages 412-420 doi: 10.1007/s11684-015-0423-x
Genetic mutations are considered to drive the development of acute myeloid leukemia (AML).mutations alone may only transform hematopoietic stem cells into pre-LSCs without causing the full-blown leukemia
Keywords: preleukemic stem cell acute myeloid leukemia relapse DNMT3A
Frontiers of Medicine 2021, Volume 15, Issue 5, Pages 728-739 doi: 10.1007/s11684-021-0833-x
Keywords: second hematopoietic stem cell transplantation acute leukemia relapse chemotherapy modified donor
Frontiers of Medicine 2023, Volume 17, Issue 3, Pages 518-526 doi: 10.1007/s11684-022-0958-6
Keywords: acute lymphoblastic leukemia child venous thromboembolism epidemiology clinical characteristic risk
Management of mantle cell leukemia with cardiac involvement leading to cardiogenic shock
Muhammad Furqan,Yamei Chen,Akintunde Akinleye,Judy Sarungbam,Alan Gass,Karen Seiter,Delong Liu
Frontiers of Medicine 2014, Volume 8, Issue 2, Pages 254-258 doi: 10.1007/s11684-014-0319-1
Keywords: mantle cell lymphoma bendamustine cardiogenic shock
Frontiers of Medicine 2022, Volume 16, Issue 1, Pages 139-149 doi: 10.1007/s11684-021-0835-8
Keywords: B-cell acute lymphoblastic leukemia bispecific antibody trispecific antibody CD19 CD20
Frontiers of Medicine 2023, Volume 17, Issue 4, Pages 685-698 doi: 10.1007/s11684-022-0942-1
Keywords: acute myeloid leukemia acyl-CoA synthetase long chain family member 5 Wnt3a palmitoylation ABT-199
AML1-ETO driven acute leukemia: insights into pathogenesis and potential therapeutic approaches
Megan A. Hatlen, Lan Wang, Stephen D. Nimer
Frontiers of Medicine 2012, Volume 6, Issue 3, Pages 248-262 doi: 10.1007/s11684-012-0206-6
Keywords: AML1-ETO mouse model leukemia t(8 21) pathway hits mutation hematopoiesis Kasumi-1 CD34+
Zhan Su, Fengyu Wu, Weiyu Hu, Xiaodan Liu, Shaoling Wu, Xianqi Feng, Zhongguang Cui, Jie Yang, Zhenguang Wang, Hongzai Guan, Hongguo Zhao, Wei Wang, Chunting Zhao, Jun Peng
Frontiers of Medicine 2017, Volume 11, Issue 3, Pages 440-444 doi: 10.1007/s11684-017-0523-x
Philadelphia chromosome-positive acute myeloid leukemia is controversial and difficult to distinguishfrom the blast phase of chronic myeloid leukemia.As a myeloid neoplasm, rare cases of this leukemia manifest multiple soft-tissue tumors or bone lytictogether with complex chromosome abnormalities, a diagnosis of Philadelphia-positive acute myeloid leukemia
Keywords: Philadelphia chromosome acute myeloid leukemia mass osteolysis positron emission tomography
Title Author Date Type Operation
Arsenic in the treatment of newly diagnosed acute promyelocytic leukemia: current status and future research
Jiong HU
Journal Article
Molecular pathogenesis of acute myeloid leukemia: A diverse disease with new perspectives
Felicitas THOL, Arnold GANSER
Journal Article
Prognostic analysis of chronic myeloid leukemia in Chinese population in an imatinib era
Haiyan He, Yang Shen, Yongmei Zhu, Saijuan Chen
Journal Article
hematopoietic stem cell transplantation to nilotinib and dasatinib for adult patients with chronic myelogenous leukemia
Lanping Xu,Huanling Zhu,Jianda Hu,Depei Wu,Hao Jiang,Qian Jiang,Xiaojun Huang
Journal Article
Molecular mechanisms of leukemia-associated protein degradation
Ying-Li WU, Guo-Qiang CHEN, Hu-Chen ZHOU,
Journal Article
Early T-cell precursor leukemia: a subtype of high risk childhood acute lymphoblastic leukemia
Meilin Ma, Xiang Wang, Jingyan Tang, Huiliang Xue, Jing Chen, Ci Pan, Hua Jiang, Shuhong Shen
Journal Article
methylation regulators endow hematopoietic stem cells with the preleukemic stem cell property, a requisite of leukemia
Yuting Tan,Han Liu,Saijuan Chen
Journal Article
unmanipulated allogeneic transplantation could be used as a salvage option for patients with relapsed acute leukemia
Journal Article
Venous thromboembolism in children with acute lymphoblastic leukemia in China: a report from the Chinese
Journal Article
Management of mantle cell leukemia with cardiac involvement leading to cardiogenic shock
Muhammad Furqan,Yamei Chen,Akintunde Akinleye,Judy Sarungbam,Alan Gass,Karen Seiter,Delong Liu
Journal Article
CD3/CD19 bispecific and novel CD3/CD19/CD20 trispecific antibodies against B-cell acute lymphoblastic leukemia: targeted immunotherapy for acute lymphoblastic leukemia
Journal Article
ACSL5, a prognostic factor in acute myeloid leukemia, modulates the activity of Wnt/-catenin signaling
Journal Article
AML1-ETO driven acute leukemia: insights into pathogenesis and potential therapeutic approaches
Megan A. Hatlen, Lan Wang, Stephen D. Nimer
Journal Article