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Chronic hepatitis B virus infection: epidemiology, prevention, and treatment in China

Rui Yu,Rong Fan,Jinlin Hou

Frontiers of Medicine 2014, Volume 8, Issue 2,   Pages 135-144 doi: 10.1007/s11684-014-0331-5

Abstract:

Chronic hepatitis B is a major health problem in China. The universal vaccination program since 1992 has changed the epidemiology of hepatitis B virus infection in China from highly to moderately endemic. The most prevalent hepatitis B virus strains in China are genotypes B and C, whereas those in western provinces are genotypes D and C/D hybrid. Chronic hepatitis B poses a heavy burden to the society in China. Different treatment strategies have been explored to improve patient outcomes in a cost-effective manner. However, antiviral drugs with a low genetic barrier to resistance are still extensively used because of the generally low income and limited resources in China. Individualized antiviral therapy is closely associated with translational medicine, which utilizes information from studies on genomics, immune biomarkers, and fibrosis. The results of these studies are crucial in further improving treatment outcomes.

Keywords： chronic hepatitis B     epidemiology     prevention     treatment    

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Exploration of Strategies for Chronic Disease Prevention and Control and Relevant System Development

Long-de Wang

Frontiers of Engineering Management 2015, Volume 2, Issue 1,   Pages 2-12 doi: 10.15302/J-FEM-2015002

Abstract: status of major chronic diseases in China, analyzing the key issues and key factors in chronic disease preventionprevious projects, this paper proposes the following recommendations as strategies for chronic disease preventionWork norms and requirements will then improve the performance and efficiency in chronic disease prevention

Keywords： chronic disease prevention and control     strategy and system construction    

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Stroke prevention: an update

Marie-Germaine Bousser

Frontiers of Medicine 2012, Volume 6, Issue 1,   Pages 22-34 doi: 10.1007/s11684-012-0178-6

Abstract: Prevention of stroke includes—as for all other diseases—a “mass approach” aimingThese measures are the basis of primary prevention but most of them have now been shown to be also effectivein secondary prevention.and various treatments addressing the specific subtypes of stroke, such as antiplatelet drugs for the preventionThere is a growing awareness of the huge evidence-to-practice gap that exists in stroke prevention largely

Keywords： stroke     prevention     vascular risk factors     cerebral infarction     cerebral hemorrhage     anti-thrombotic drugs    

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Construction of the vessel-collateral theory and its guidance for prevention and treatment of vasculopathy

Yiling Wu

Frontiers of Medicine 2011, Volume 5, Issue 2,   Pages 118-122 doi: 10.1007/s11684-011-0140-z

Abstract: medicine, vessel-collateral theory was constructed systematically, which was important to improving preventionThese research have improved prevention and treatment level of major vascular system diseases.

Keywords： vessel-collateral theory     vasculopathy     prevention and treatment    

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Health: a dream from reality to the future

Chunsong Hu,Qinghua Wu

Frontiers of Medicine 2016, Volume 10, Issue 2,   Pages 233-235 doi: 10.1007/s11684-016-0444-0

Abstract: person’s and his/her family’s happiness, health requires not only primary and secondary prevention, but also policy prevention, that is to say, grade-zero prevention. As a new preventive strategy, the policy prevention will help improve people’s health

Keywords： health promotion     primary and secondary prevention     policy prevention     infectious disease     non-communicable    

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Taizhou’s COVID-19 prevention and control experience with telemedicine features

Cenyi Shao, Shijian Li, Feng Zhu, Dahai Zhao, Hui Shao, Haixiao Chen, Zhiruo Zhang

Frontiers of Medicine 2020, Volume 14, Issue 4,   Pages 506-510 doi: 10.1007/s11684-020-0811-8

Abstract: Taizhou led in opening the “COVID-19 Prevention and Treatment Special Line” in China, which is conduciveWe summarize Taizhou’s COVID-19 prevention and control experience with telemedicine features, with a

Keywords： COVID-19     telemedicine     prevention experience    

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Human microbiome and prostate cancer development: current insights into the prevention and treatment

Solmaz Ohadian Moghadam, Seyed Ali Momeni

Frontiers of Medicine 2021, Volume 15, Issue 1,   Pages 11-32 doi: 10.1007/s11684-019-0731-7

Abstract: Furthermore, we discuss strategies to target the microbiome for risk assessment, prevention, and treatment

Keywords： microbiome     prostate cancer     prevention     treatment     molecular pathological epidemiology (MPE)     biomarker    

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Disaster prevention and reduction in Anthropocene

Sha Chen,Bo Tao,Wei Ren

Frontiers of Environmental Science & Engineering 2016, Volume 10, Issue 5, doi: 10.1007/s11783-016-0882-6

Abstract: vulnerabilities and risks, and build resilience through implementing effective measures of disaster prevention

Keywords： natural disasters     global change     Sendai Framework    

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Developments in cancer prevention and treatment using traditional Chinese medicine

Hongsheng Lin, Jie Liu, Ying Zhang

Frontiers of Medicine 2011, Volume 5, Issue 2,   Pages 127-133 doi: 10.1007/s11684-011-0137-7

Abstract: Currently, TCM plays an indispensable role in cancer prevention and treatment.

Keywords： traditional Chinese medicine (TCM)     cancer    

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China released the Action Plan on Prevention and Control of Soil Pollution

Fang Zhang,Guanghe Li

Frontiers of Environmental Science & Engineering 2016, Volume 10, Issue 4, doi: 10.1007/s11783-016-0867-5

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Prevention and control of zoonoses at their source: from the Chinese perspective

Songtao YANG,Yuwei GAO,Jun QIAN,Quan LIU,Xuexing ZHENG,Hualei WANG,Zhiping XIA,Xianzhu XIA

Frontiers of Agricultural Science and Engineering 2014, Volume 1, Issue 2,   Pages 96-103 doi: 10.15302/J-FASE-2014030

Abstract: devised new strategies and has taken measures to deal with the challenges of these diseases, and the prevention

Keywords： zoonosis     prevention and control     joint prevention and control    

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China’s Ministry of Environmental Protection Adopted Draft Amendment to the Law on Prevention and Control

Fu Sun,Yi Liu

Frontiers of Environmental Science & Engineering 2016, Volume 10, Issue 6, doi: 10.1007/s11783-016-0890-6

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Preliminary results of gentamycin combined with sodium bicarbonate for prevention of irinotecan-induced

Qi MEI MM, Zhe CAO MM, Hua XIONG MD, Yuan CHEN MD,

Frontiers of Medicine 2009, Volume 3, Issue 4,   Pages 470-474 doi: 10.1007/s11684-009-0077-7

Abstract: this paper was to observe the clinical effect of gentamycin combined with sodium bicarbonate for the preventionA total of 98 patients with stage IV cancers were recruited and divided into a prevention group (52 patientsThe prevention group received gentamycin and sodium bicarbonate before the use of irinotecan for 4 days; the control group did not receive any prevention.significantly higher stool pH ( < 0.001), while the incidence of diarrhea by irinotecan was reduced (prevention

Keywords： irinotecan     diarrhea     gentamycin     sodium bicarbonate     prevention    

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Strategies for Disaster Prevention and Mitigation in Safety and Resilient Cities

Fang Yudong , Wang Wen , Zhang Zhi , Bian Lu

Strategic Study of CAE 2023, Volume 25, Issue 1,   Pages 1-9 doi: 10.15302/J-SSCAE-2023.01.009

Abstract: The construction of safety resilient cities focuses on urban disaster prevention and mitigation and canConsidering the demand for urban disaster prevention, mitigation, and safe development,?this study reviews the problems existing in urban disaster prevention and mitigation and analyzed theconstruction of disaster prevention and mitigation infrastructure to improve urban fortification; andof technologies and skilled professionals for disaster prevention and mitigation to improve risk governance

Keywords： safety and resilient city     risk prevention and control     public safety     disaster prevention and mitigation    

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Epigenetics and environmental health

Frontiers of Medicine doi: 10.1007/s11684-023-1038-2

Abstract: Epigenetic modifications including DNA methylation, histone modifications, chromatin remodeling, and RNA modifications complicate gene regulation and heredity and profoundly impact various physiological and pathological processes. In recent years, accumulating evidence indicates that epigenetics is vulnerable to environmental changes and regulates the growth, development, and diseases of individuals by affecting chromatin activity and regulating gene expression. Environmental exposure or induced epigenetic changes can regulate the state of development and lead to developmental disorders, aging, cardiovascular disease, Alzheimer’s disease, cancers, and so on. However, epigenetic modifications are reversible. The use of specific epigenetic inhibitors targeting epigenetic changes in response to environmental exposure is useful in disease therapy. Here, we provide an overview of the role of epigenetics in various diseases. Furthermore, we summarize the mechanism of epigenetic alterations induced by different environmental exposures, the influence of different environmental exposures, and the crosstalk between environmental variation epigenetics, and genes that are implicated in the body’s health. However, the interaction of multiple factors and epigenetics in regulating the initiation and progression of various diseases complicates clinical treatments. We discuss some commonly used epigenetic drugs targeting epigenetic modifications and methods to prevent or relieve various diseases regulated by environmental exposure and epigenetics through diet.

Keywords： epigenetics     environmental exposure     health     prevention and therapy    

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Title Author Date Type Operation

Chronic hepatitis B virus infection: epidemiology, prevention, and treatment in China

Rui Yu,Rong Fan,Jinlin Hou

Journal Article

Exploration of Strategies for Chronic Disease Prevention and Control and Relevant System Development

Long-de Wang

Journal Article

Stroke prevention: an update

Marie-Germaine Bousser

Journal Article

Construction of the vessel-collateral theory and its guidance for prevention and treatment of vasculopathy

Yiling Wu

Journal Article

Health: a dream from reality to the future

Chunsong Hu,Qinghua Wu

Journal Article

Taizhou’s COVID-19 prevention and control experience with telemedicine features

Cenyi Shao, Shijian Li, Feng Zhu, Dahai Zhao, Hui Shao, Haixiao Chen, Zhiruo Zhang

Journal Article

Human microbiome and prostate cancer development: current insights into the prevention and treatment

Solmaz Ohadian Moghadam, Seyed Ali Momeni

Journal Article

Disaster prevention and reduction in Anthropocene

Sha Chen,Bo Tao,Wei Ren

Journal Article

Developments in cancer prevention and treatment using traditional Chinese medicine

Hongsheng Lin, Jie Liu, Ying Zhang

Journal Article

China released the Action Plan on Prevention and Control of Soil Pollution

Fang Zhang,Guanghe Li

Journal Article

Prevention and control of zoonoses at their source: from the Chinese perspective

Songtao YANG,Yuwei GAO,Jun QIAN,Quan LIU,Xuexing ZHENG,Hualei WANG,Zhiping XIA,Xianzhu XIA

Journal Article

China’s Ministry of Environmental Protection Adopted Draft Amendment to the Law on Prevention and Control

Fu Sun,Yi Liu

Journal Article

Preliminary results of gentamycin combined with sodium bicarbonate for prevention of irinotecan-induced

Qi MEI MM, Zhe CAO MM, Hua XIONG MD, Yuan CHEN MD,

Journal Article

Strategies for Disaster Prevention and Mitigation in Safety and Resilient Cities

Fang Yudong , Wang Wen , Zhang Zhi , Bian Lu

Journal Article

Epigenetics and environmental health

Journal Article